Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | OGG1 | O15527 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879053 | 1.00 | TBXAS1 (0.49) | TBXAS1LMNAOGG1ALDH1A1MAPT | |
| SCHEMBL6879049 | 1.00 | TBXAS1 (0.49) | TBXAS1LMNAOGG1ALDH1A1MAPT | |
| SCHEMBL6154989 | 0.84 | TBXAS1 (0.48) | TBXAS1LMNAOGG1ALDH1A1MAPT | |
| SCHEMBL6154994 | 0.84 | TBXAS1 (0.48) | TBXAS1LMNAOGG1ALDH1A1MAPT | |
| SCHEMBL6154999 | 0.84 | TBXAS1 (0.48) | TBXAS1LMNAOGG1ALDH1A1MAPT | |
| SCHEMBL6156377 | 0.83 | CA12 (0.49) | TBXAS1ALDH1A1MAPTPARP1KDM4E | |
| SCHEMBL6154738 | 0.83 | CA12 (0.49) | TBXAS1ALDH1A1MAPTPARP1KDM4E | |
| SCHEMBL6154731 | 0.83 | CA12 (0.49) | TBXAS1ALDH1A1MAPTPARP1KDM4E | |
| SCHEMBL16386232 | 0.82 | ALDH1A1 (0.50) | OGG1ALDH1A1MAPTPARP1KDM4E | |
| SCHEMBL27437283 | 0.79 | NPC1 (0.50) | ALDH1A1MAPTKDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |