Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879056 | 1.00 | MCHR1 (0.44) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6878317 | 0.91 | CCNC (0.53) | CCNCCDK8KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL6878327 | 0.91 | CCNC (0.53) | CCNCCDK8KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL6877094 | 0.90 | NPC1 (0.53) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877102 | 0.90 | NPC1 (0.53) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6878755 | 0.90 | MCHR1 (0.40) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6878762 | 0.90 | MCHR1 (0.40) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6878058 | 0.88 | MEN1 (0.58) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6878062 | 0.88 | MEN1 (0.58) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6877906 | 0.87 | EPHX2 (0.48) | MCHR1ADRA2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |