SCHEMBL6879185

SCHEMBL6879185

Cc1ccc(S(=O)(=O)OSc2ccc3oc4ccccc4c(=S)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 1/20 0.40
MAOB P27338 3/20 0.37
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
PIK3CG P48736 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TNKS O95271 1/20 0.34
PARP1 P09874 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3520236 0.79 BCAT1 (0.42) BCAT1MAOBPIK3CDPIK3CAPIK3CB
SCHEMBL5110944 0.78 SMN1; SMN2 (0.35) BCAT1KDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL3523837 0.77 LMNA (0.40) BCAT1MAOBPIK3CDPIK3CAPIK3CB
SCHEMBL5042080 0.73 SMN1; SMN2 (0.32) HPGDALDH1A1SMN1; SMN2MAPTHTT
SCHEMBL1258329 0.72 MAOB (0.50) MAOBKDM4EHPGDALDH1A1SMN1; SMN2
SCHEMBL23241350 0.72 DNMT1 (0.52) NPSR1ALDH1A1SMN1; SMN2MAPTHTT
SCHEMBL3520234 0.72 BCAT1 (0.42) BCAT1MAOBPIK3CDPIK3CAPIK3CB
SCHEMBL5049209 0.72 BCAT1 (0.44) BCAT1MAOBPIK3CDPIK3CAPIK3CB
SCHEMBL3519030 0.71 LMNA (0.39) BCAT1MAOBPIK3CDPIK3CAPIK3CB
SCHEMBL3523833 0.70 BCAT1 (0.40) BCAT1MAOBPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed