Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879286 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDRECQLRAB9A | |
| SCHEMBL6878890 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDRECQLRAB9A | |
| SCHEMBL6878899 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDRECQLRAB9A | |
| SCHEMBL6875065 | 0.90 | MCHR1 (0.42) | ALDH1A1MAPTKMT2ALMNAADRA2A | |
| SCHEMBL6875058 | 0.90 | MCHR1 (0.42) | ALDH1A1MAPTKMT2ALMNAADRA2A | |
| SCHEMBL6867788 | 0.89 | MCHR1 (0.42) | ALDH1A1MAPTRAB9AKMT2AADRA2A | |
| SCHEMBL6867783 | 0.89 | MCHR1 (0.42) | ALDH1A1MAPTRAB9AKMT2AADRA2A | |
| SCHEMBL6876990 | 0.89 | MCHR1 (0.42) | ALDH1A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL6876996 | 0.89 | MCHR1 (0.42) | ALDH1A1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL6461399 | 0.88 | MCHR1 (0.45) | ALDH1A1MAPTRAB9ALMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |