Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881282 | 0.88 | POLB (0.43) | ALDH1A1POLBHPGDMTNR1AMTNR1B | |
| SCHEMBL6171029 | 0.76 | HDAC1 (0.41) | MTNR1AMTNR1B | |
| SCHEMBL27721793 | 0.76 | PPARA (0.39) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6879525 | 0.75 | MEN1 (0.47) | ALDH1A1KMT2APOLBHPGD | |
| SCHEMBL2635979 | 0.75 | CYP4F2 (0.50) | TAAR1 | |
| SCHEMBL25379733 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1KMT2APOLBHPGD | |
| SCHEMBL18294034 | 0.74 | AOC2 (0.47) | ALDH1A1KMT2APOLB | |
| SCHEMBL8008498 | 0.74 | RAB9A (0.50) | — | |
| SCHEMBL3235704 | 0.73 | CYP1A2 (0.49) | — | |
| SCHEMBL19745618 | 0.73 | CA12 (0.40) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |