Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18500639 | 0.97 | KDM4E (0.49) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL6881489 | 0.87 | KDM4E (0.41) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL11171580 | 0.85 | KDM4E (0.50) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL14341650 | 0.84 | MAPT (0.68) | MAPTCA1CA2CA12CA7 | |
| SCHEMBL644054 | 0.84 | CA1 (0.48) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL6881492 | 0.82 | MAPT (0.36) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL6154971 | 0.82 | PLA2G2A (0.57) | POLBNFKB1NFKB2RELATDP1 | |
| SCHEMBL3176817 | 0.82 | KDM4E (0.54) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL1989863 | 0.81 | MAPT (0.54) | MAPTKDM4ECA1CA2CA12 | |
| SCHEMBL6243324 | 0.80 | CA1 (0.48) | MAPTKDM4ECA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |