Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034423 | 0.96 | PLA2G2A (0.53) | PLA2G2AKMT2AMEN1PLA2G4BBRD4 | |
| SCHEMBL6155465 | 0.86 | MRGPRX4 (0.46) | PLA2G2AKMT2AMEN1PLA2G4BBRD4 | |
| SCHEMBL2655120 | 0.84 | PLA2G2A (0.65) | PLA2G2AKMT2AMEN1PLA2G4BBRD4 | |
| SCHEMBL12940638 | 0.83 | PLA2G4B (0.64) | PLA2G4BTP53PKMSMN1; SMN2TSHR | |
| SCHEMBL6879558 | 0.82 | MAPT (0.47) | PLA2G2AKMT2AMEN1NFKB1NFKB2 | |
| SCHEMBL8751920 | 0.82 | NQO1 (0.46) | PLA2G2ATP53RELASMN1; SMN2TDP1 | |
| SCHEMBL2562354 | 0.81 | PLA2G2A (0.56) | PLA2G2AKMT2AMEN1PKMMRGPRX4 | |
| SCHEMBL3184334 | 0.80 | PLA2G2A (0.59) | PLA2G2AKMT2AMEN1PLA2G4BBRD4 | |
| SCHEMBL6155467 | 0.80 | PLA2G2A (0.40) | PLA2G2AKMT2AMEN1PLA2G4BBRD4 | |
| SCHEMBL18500639 | 0.79 | KDM4E (0.49) | KMT2AMEN1CREBBPNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |