Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686800 | 0.93 | PPARG (0.41) | PPARGFFAR1NPSR1RXFP1CTSA | |
| SCHEMBL27741938 | 0.91 | SMN1; SMN2 (0.42) | NPSR1RXFP1CTSASMN1; SMN2 | |
| SCHEMBL687967 | 0.91 | SMN1; SMN2 (0.42) | NPSR1RXFP1CTSASMN1; SMN2 | |
| SCHEMBL688409 | 0.90 | PPARG (0.42) | PPARGFFAR1NPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL686965 | 0.88 | PPARG (0.40) | PPARGFFAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL687858 | 0.88 | MEN1 (0.37) | PPARGFFAR1PYGLNPSR1RXFP1 | |
| SCHEMBL693144 | 0.87 | KDM4E (0.37) | FFAR1PYGLNPSR1RXFP1CTSA | |
| SCHEMBL688543 | 0.87 | SMN1; SMN2 (0.38) | PPARGNPSR1RXFP1CTSASMN1; SMN2 | |
| SCHEMBL688875 | 0.87 | SMN1; SMN2 (0.37) | PPARGFFAR1NPSR1RXFP1CTSA | |
| SCHEMBL27741949 | 0.87 | PPARG (0.38) | PPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |