Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688464 | 0.90 | MEN1 (0.40) | PPARGPTGER3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL688254 | 0.90 | SMN1; SMN2 (0.44) | PPARGPTGER3RXFP1TP53MAPT | |
| SCHEMBL687964 | 0.90 | PPARG (0.40) | PPARGRXFP1FFAR1SMN1; SMN2CYP1A2 | |
| SCHEMBL686800 | 0.89 | PPARG (0.41) | PPARGRXFP1FFAR1SMN1; SMN2CYP3A4 | |
| SCHEMBL686509 | 0.86 | MAPT (0.41) | PPARGPTGER3RXFP1TP53MAPT | |
| SCHEMBL687744 | 0.86 | PTGER3 (0.43) | PTGER3SLC16A3SLC16A1MCTS1RXFP1 | |
| SCHEMBL688605 | 0.86 | MEN1 (0.41) | PPARGPTGER3SLC16A3SLC16A1MCTS1 | |
| SCHEMBL687999 | 0.85 | SLC16A3 (0.42) | SLC16A3SLC16A1MCTS1TP53FFAR1 | |
| SCHEMBL686808 | 0.85 | CTSA (0.42) | PPARGPTGER3RXFP1TP53MAPT | |
| SCHEMBL687213 | 0.85 | MAPT (0.43) | PPARGPTGER3RXFP1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |