Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879769 | 1.00 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6880426 | 0.93 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6880420 | 0.93 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6867249 | 0.91 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6867254 | 0.91 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6878137 | 0.89 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6878131 | 0.89 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6867923 | 0.86 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6867919 | 0.86 | MCHR1 (0.45) | MCHR1ADRA2ANPY5RHRH1HTR2B | |
| SCHEMBL6874307 | 0.86 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |