Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | SQLE | Q14534 | 5/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2145855 | 0.98 | ALDH1A1 (0.61) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL2145863 | 0.98 | ALDH1A1 (0.61) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL2146239 | 0.98 | ALDH1A1 (0.61) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL6882595 | 0.93 | KMT2A (0.67) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL6882598 | 0.93 | KMT2A (0.67) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL28069711 | 0.93 | KMT2A (0.67) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| Phosphoric Acid SCHEMBL2454064 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KMT2A | |
| SCHEMBL28959116 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| Citral SCHEMBL2419580 | 0.81 | ALDH1A1 (0.84) | ALDH1A1KMT2AALOX15MEN1CYP3A4 | |
| Citral SCHEMBL2419581 | 0.81 | ALDH1A1 (0.84) | ALDH1A1KMT2AALOX15MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1351922-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055480-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | MAX PLANCK GESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | CORO1C, CORO1A, AGER | ALDH1A1 3951/4885KMT2A 2207/4885ALOX15 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.