Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 6/20 | 0.37 |
| ▸ | PRKX | P51817 | 6/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 5/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 5/20 | 0.37 |
| ▸ | GSK3A | P49840 | 5/20 | 0.37 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.37 |
| ▸ | PRKG2 | Q13237 | 4/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | SGK2 | Q9HBY8 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879912 | 1.00 | HDAC1 (0.42) | HDAC1HDAC6MAPTLMNAKIF11 | |
| SCHEMBL6879903 | 1.00 | HDAC1 (0.42) | HDAC1HDAC6MAPTLMNAKIF11 | |
| SCHEMBL6877827 | 0.82 | ATM (0.39) | HDAC1MAP4K4ERN1 | |
| SCHEMBL6877820 | 0.82 | ATM (0.39) | HDAC1MAP4K4ERN1 | |
| SCHEMBL6877823 | 0.82 | ATM (0.39) | HDAC1MAP4K4ERN1 | |
| SCHEMBL6877224 | 0.82 | MKNK1 (0.54) | MAPTLMNAKIF11SMN1; SMN2 | |
| SCHEMBL6877227 | 0.82 | MKNK1 (0.54) | MAPTLMNAKIF11SMN1; SMN2 | |
| SCHEMBL6877229 | 0.82 | MKNK1 (0.54) | MAPTLMNAKIF11SMN1; SMN2 | |
| SCHEMBL6878376 | 0.80 | CYP2D6 (0.43) | MAPTPRKACAPRKXROCK1CLK4 | |
| SCHEMBL6878371 | 0.80 | CYP2D6 (0.43) | MAPTPRKACAPRKXROCK1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |