Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880098 | 1.00 | MAPT (0.53) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL2945906 | 0.89 | MAPT (0.59) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL2945907 | 0.89 | MAPT (0.59) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL11325124 | 0.84 | MAPT (0.55) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL11325121 | 0.84 | MAPT (0.55) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36139 | 0.84 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36375 | 0.84 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL6885967 | 0.84 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36140 | 0.84 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL7809914 | 0.81 | MAPT (0.67) | MAPTCACNA1BAPBA1APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048215-A | Process for preparation of trans-chrysanthemates | ROUSSEL ULCAF (FR) | 1977-09-13 | — | — | US | claimed |
| WO-2016024287-A1 | AN IMPROVED PROCESS FOR PREPARING PURE MINODRONIC ACID AND INTERMEDIATES THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2016-02-18 | — | — | WO | disclosed |
| US-20040248913-A1 | (Pyridinyl and pyrimidyl) trienoic acid derivatives as retinoid x receptor modulators | LIGAND PHARMACEUTICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1414450-A1 | (PYRIDINYL AND PYRIMIDYL)TRIENOIC ACID DERIVATIVES AS RETINOID X RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003007950-A1 | (PYRIDINYL AND PYRIMIDYL) TRIENOIC ACID DERIVATIVES AS RETINOID X RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |
| US-4266075-A | Bicyclic aldehyde derivatives, their use as perfuming and flavoring ingredients and process for their preparation | FIRMENICH, S.A. (CH) | 1981-05-05 | — | — | US | disclosed |
| US-4218347-A | Bicyclic aldehyde perfuming and flavoring ingredients | FIRMENICH SA (CH) | 1980-08-19 | — | — | US | disclosed |
| US-4048215-A | Process for preparation of trans-chrysanthemates | ROUSSEL ULCAF (FR) | 1977-09-13 | — | — | US | disclosed |
| US-4048215-A | Process for preparation of trans-chrysanthemates | ROUSSEL ULCAF (FR) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248913-A1 | (Pyridinyl and pyrimidyl) trienoic acid derivatives as retinoid x receptor modulators | TSHR, THRA, RXRA | MAPT 4803/4885CACNA1B 4832/4885APBA1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.