Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464914 | 1.00 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RALDH1A1MEN1 | |
| SCHEMBL6878737 | 0.92 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RALDH1A1MEN1 | |
| SCHEMBL6456397 | 0.92 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RALDH1A1MEN1 | |
| SCHEMBL6875477 | 0.90 | KCNH2 (0.43) | MCHR1ADRA2ANPY5RACHEDRD2 | |
| SCHEMBL6875484 | 0.90 | KCNH2 (0.43) | MCHR1ADRA2ANPY5RACHEDRD2 | |
| SCHEMBL6875677 | 0.90 | MCHR1 (0.41) | MCHR1ADRA2ANPY5RALDH1A1ACHE | |
| SCHEMBL6460055 | 0.90 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RALDH1A1KDM4E | |
| SCHEMBL6874340 | 0.90 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RALDH1A1KDM4E | |
| SCHEMBL6875669 | 0.90 | MCHR1 (0.41) | MCHR1ADRA2ANPY5RALDH1A1ACHE | |
| SCHEMBL6460406 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |