Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875677 | 1.00 | MCHR1 (0.41) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6459873 | 0.94 | APLNR (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6874596 | 0.94 | APLNR (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6875484 | 0.91 | KCNH2 (0.43) | MCHR1ADRA2ANPY5RKCNH2ACHE | |
| SCHEMBL6875477 | 0.91 | KCNH2 (0.43) | MCHR1ADRA2ANPY5RKCNH2ACHE | |
| SCHEMBL6880166 | 0.90 | MCHR1 (0.49) | MCHR1ADRA2ANPY5RACHEBACE1 | |
| SCHEMBL6876140 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RAURKBACHE | |
| SCHEMBL6877329 | 0.90 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6877339 | 0.90 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RCNR1KCNH2 | |
| SCHEMBL6876132 | 0.90 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RAURKBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |