Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678436 | 0.79 | P2RX7 (0.51) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4377982 | 0.78 | P2RX7 (0.48) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1677912 | 0.78 | P2RX7 (0.50) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1677845 | 0.77 | P2RX7 (0.47) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1678665 | 0.77 | P2RX7 (0.49) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1678506 | 0.77 | P2RX7 (0.46) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1678213 | 0.76 | SMN1; SMN2 (0.66) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1677863 | 0.76 | P2RX7 (0.44) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29742245 | 0.76 | P2RX7 (0.49) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1679345 | 0.76 | P2RX7 (0.48) | P2RX7EPHX2EPHX1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457205-A1 | ANGIOGENESIS INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-09-15 | — | — | EP | disclosed |