⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025313 | 0.80 | — | — | |
| SCHEMBL1101400 | 0.75 | — | — | |
| SCHEMBL1208896 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29471655 | 0.73 | — | — | |
| SCHEMBL3949066 | 0.71 | — | — | |
| SCHEMBL4723235 | 0.69 | — | — | |
| SCHEMBL861254 | 0.66 | — | — | |
| SCHEMBL8917855 | 0.62 | — | — | |
| SCHEMBL15013669 | 0.61 | DPP7 (0.36) | — | |
| SCHEMBL6213386 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472277-A1 | FAP-ACTIVATED ANTI-TUMOR COMPOUNDS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-20030211979-A1 | FAP-activated anti-tumor compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-11-13 | — | — | US | disclosed |
| WO-2003064454-A1 | FAP-ACTIVATED ANTI-TUMOR COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2003-08-07 | — | — | WO | disclosed |
| EP-1333033-A1 | FAP-activated anti-tumor compounds | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002038590-A1 | FAP-ALPHA-ACTIVATED ANTI-TUMOR COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-05-16 | — | — | WO | disclosed |