Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491446 | 0.84 | P2RX7 (0.39) | P2RX7 | |
| Hydrochloric Acid SCHEMBL3670799 | 0.81 | P2RX7 (0.51) | P2RX7CHRNA7DRD3DRD2 | |
| SCHEMBL24835188 | 0.80 | P2RX7 (0.37) | P2RX7TMEM97SIGMAR1CHRNA7ALDH1A1 | |
| SCHEMBL4949268 | 0.75 | CFB (0.36) | CHRNA7DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL3670800 | 0.70 | P2RX7 (0.41) | P2RX7SIGMAR1CHRNA7DRD3DRD2 | |
| SCHEMBL24427032 | 0.70 | P2RX7 (0.41) | P2RX7CHRNA7DRD3DRD2 | |
| SCHEMBL21988581 | 0.70 | P2RX7 (0.47) | P2RX7CHRNA7DRD3ALDH1A1DRD2 | |
| SCHEMBL2009102 | 0.69 | DRD2 (0.53) | DRD3DRD2 | |
| SCHEMBL7587091 | 0.69 | P2RX7 (0.41) | P2RX7DRD3DRD2MEN1KMT2A | |
| SCHEMBL21590238 | 0.68 | P2RX7 (0.39) | P2RX7CHRNA7ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |