Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13173290 | 0.89 | PKM (0.57) | PKMHTTPOLBTSHRMAPT | |
| SCHEMBL1230603 | 0.83 | KMT2A (0.56) | PKMHTTTSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2290641 | 0.82 | KMT2A (0.56) | PKMHTTTSHRMAPTALDH1A1 | |
| SCHEMBL8592338 | 0.82 | HTT (0.49) | PKMHTTPOLBTSHRMAPT | |
| Acetic Acid SCHEMBL1232023 | 0.80 | KMT2A (0.55) | PKMHTTTSHRMAPTNPC1 | |
| SCHEMBL13173293 | 0.77 | PKM (0.53) | PKMHTTPOLBTSHRMAPT | |
| SCHEMBL31347921 | 0.77 | MAPT (0.55) | PKMHTTPOLBTSHRMAPT | |
| SCHEMBL2295550 | 0.75 | KMT2A (0.60) | PKMHTTTSHRMAPTRAB9A | |
| SCHEMBL6207754 | 0.74 | KMT2A (0.71) | PKMTSHRNPC1RAB9AAPOBEC3A | |
| SCHEMBL1668350 | 0.74 | KMT2A (0.56) | PKMHTTPOLBTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016016-A1 | PROCESSES FOR THE PREPARATION OF VARDENAFIL | RANBAXY LABORATORIES LIMITED (IN) | 2011-02-10 | — | — | WO | disclosed |