SCHEMBL6880561

SCHEMBL6880561

CC(C)(C)C(=O)CC(=O)C(F)(F)C(F)(F)C(F)(F)F.CC(C)(C)C(=O)CC(=O)C(F)(F)C(F)(F)C(F)(F)F.CC(C)(C)C(=O)CC(=O)C(F)(F)C(F)(F)C(F)(F)F.[Eu]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LIPA P38571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28746989 1.00 THRB (0.33) THRBLIPA
SCHEMBL20453952 0.98 THRB (0.34) THRBLIPA
SCHEMBL196683 0.98 THRB (0.34) THRBLIPA
SCHEMBL9776033 0.96 THRB (0.33) THRBLIPA
SCHEMBL29093088 0.96 THRB (0.33) THRBLIPA
SCHEMBL15817269 0.96 THRB (0.33) THRBLIPA
SCHEMBL10919609 0.96 THRB (0.33) THRBLIPA
SCHEMBL28467362 0.96 THRB (0.33) THRBLIPA
SCHEMBL8194781 0.96 THRB (0.33) THRBLIPA
SCHEMBL8994614 0.96 THRB (0.33) THRBLIPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4176918-A Fluorescent liquid crystal display TEMPLE UNIVERSITY (US) 1979-12-04 US claimed
CN-117603035-B Chalcone derivative and preparation method and application thereof 南开大学 2025-02-11 CN disclosed
CN-119186422-A Preparation method of microsphere composition used in photo-excitation chemiluminescence immunoassay technology 北京艾维镝生物技术有限责任公司 2024-12-27 CN disclosed
CN-116673067-B High-purity alumina active sphere carrier and preparation method thereof 扬州中天利新材料股份有限公司 2024-12-06 CN disclosed
CN-118873822-A Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-11-01 CN disclosed
CN-118791456-A 3', 8-Disubstituted quercetin derivatives, preparation method and application thereof 上海医药工业研究院有限公司 2024-10-18 CN disclosed
CN-115746010-B Synthesis of flavonoid derivative and pharmaceutical application thereof 南开大学 2024-10-15 CN disclosed
CN-116942656-B Application of naringenin derivative in preparation of anti-pancreatitis medicine 四川大学华西医院 2024-09-17 CN disclosed
CN-117603175-B Chalcone derivative with benzopyran structure, and preparation method and application thereof 南开大学 2024-08-06 CN disclosed
CN-115636809-B Synthesis and pharmaceutical application of chalcone derivatives 南开大学 2024-06-11 CN disclosed
US-11479537-B2 T-type calcium channel inhibitor KINKI UNIVERSITY (JP) 2022-10-25 US disclosed
CN-114752374-A Preparation method of microsphere composition used in homogeneous chemiluminescence immunoassay technology 北京艾维镝生物技术有限责任公司 2022-07-15 CN disclosed
CN-114746740-A Luminescence imaging for sensing C2感官有限公司 2022-07-12 CN disclosed
CN-107298667-B Method for synthesizing icaritin 北京盛诺基医药科技股份有限公司 2020-09-08 CN disclosed
US-6723454-B2 Luminescent device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-04-20 US disclosed
EP-1090087-B1 LUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-08-13 EP disclosed
US-20030012979-A1 Luminescent device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2003-01-16 US disclosed
EP-1090087-A1 LUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 2001-04-11 EP disclosed
WO-2000064996-A1 LUMINESCENT DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2000-11-02 WO disclosed
US-4176918-A Fluorescent liquid crystal display TEMPLE UNIVERSITY (US) 1979-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11479537-B2 T-type calcium channel inhibitor CACNA1H, CACNA1I, CACNA1G THRB 237/4885LIPA 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.