SCHEMBL6880704

SCHEMBL6880704

C=CC(=O)Nc1cc(C)cc(O)c1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 9/20 0.58
LMNA P02545 2/20 0.46
F13A1 P00488 1/20 0.44
TGM1 P22735 1/20 0.44
TGM3 Q08188 1/20 0.44
BTK Q06187 1/20 0.43
ALDH1A1 P00352 1/20 0.41
EGFR P00533 3/20 0.40
ITK Q08881 2/20 0.40
HCAR1 Q9BXC0 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
ERBB2 P04626 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28114474 0.89 TGM2 (0.66) TGM2LMNAF13A1TGM1TGM3
SCHEMBL13921963 0.87 TGM2 (0.55) TGM2LMNAF13A1TGM1TGM3
SCHEMBL16096107 0.81 TGM2 (0.58) TGM2LMNAF13A1TGM1TGM3
SCHEMBL27801542 0.79 TGM2 (0.58) TGM2LMNAF13A1TGM1TGM3
SCHEMBL30935106 0.78 TGM2 (0.53) TGM2LMNAF13A1TGM1TGM3
SCHEMBL16053417 0.78 TGM2 (0.64) TGM2LMNAF13A1TGM1TGM3
SCHEMBL13061716 0.77 LMNA (0.76) LMNAALDH1A1HCAR1
SCHEMBL18790328 0.77 TGM2 (0.51) TGM2LMNAF13A1TGM1TGM3
SCHEMBL18778619 0.77 TGM2 (0.59) TGM2LMNAALDH1A1EGFR
SCHEMBL5987435 0.76 LMNA (0.50) LMNAALDH1A1HCAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-0972776-B1 A phosphine sulfide, a manufacturing process therefor and a use thereof MITSUI CHEMICALS INC (JP) 2003-04-23 EP disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6153794-A Phosphine sulfide, a manufacturing process therefor and use thereof MITSUI CHEMICALS, INC. (JP) 2000-11-28 US disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0972776-A1 A phosphine sulfide, a manufacturing process therefor and a use thereof Mitsui Chemicals, Inc. (JP) 2000-01-19 EP disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed