Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495469 | 0.89 | CYP19A1 (0.54) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL7358307 | 0.87 | LOXL2 (0.56) | KDM4EMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL15155439 | 0.84 | CYP19A1 (0.53) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL3136413 | 0.83 | KDM4E (0.56) | CYP19A1TBXAS1KDM4EMAPTMEN1 | |
| SCHEMBL5542601 | 0.82 | CYP19A1 (0.51) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL6115223 | 0.82 | CYP19A1 (0.51) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL828039 | 0.82 | CYP19A1 (0.51) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL4242510 | 0.81 | TLR8 (0.50) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL5543653 | 0.81 | CYP19A1 (0.50) | CYP19A1TBXAS1CHRM1KDM4EMAPT | |
| SCHEMBL11648609 | 0.80 | POLB (0.43) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1451009-A | Glucocortiocoid-selective antinflammatory agents | ABBOTT LAB (US) | 2003-10-22 | — | — | CN | claimed |
| CN-1119348-C | glucocorticoid derivatives, compositions and uses thereof | ABBOTT INC (US) | 2003-08-27 | — | — | CN | claimed |
| EP-1299392-A2 | GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS | Abbott Laboratories (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002002565-A2 | GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 2002-01-10 | — | — | WO | claimed |
| CN-1296486-A | Glucocorticoid-selective anti-inflammatory agents | ABBOTT LAB (US) | 2001-05-23 | — | — | CN | claimed |
| WO-2021138298-A1 | MALT1 MODULATORS AND USES THEREOF | RHEOS MEDICINES, INC. (US) | 2021-07-08 | — | — | WO | disclosed |
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| CN-1451009-A | Glucocortiocoid-selective antinflammatory agents | ABBOTT LAB (US) | 2003-10-22 | — | — | CN | disclosed |
| CN-1119348-C | glucocorticoid derivatives, compositions and uses thereof | ABBOTT INC (US) | 2003-08-27 | — | — | CN | disclosed |
| CN-1422953-A | Gene sequence of Japanese shistosome China mainland strain gynecophoric canal protein | SHANGHAI DOMESTIC ANIMAL PARAS (CN) | 2003-06-11 | — | — | CN | disclosed |
| CN-1296486-A | Glucocorticoid-selective anti-inflammatory agents | ABBOTT LAB (US) | 2001-05-23 | — | — | CN | disclosed |