Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6877387

Cc1ccc(S(=O)(=O)Oc2cc3oc(=O)ccc3cc2C)cc1.S

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.54
CA9 Q16790 4/20 0.54
CA1 P00915 3/20 0.54
MAOB P27338 1/20 0.50
ALDH1A1 P00352 3/20 0.48
MCL1 Q07820 3/20 0.47
CA2 P00918 1/20 0.45
GLA P06280 4/20 0.45
GAA P10253 4/20 0.45
KDM4E B2RXH2 3/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
PKM P14618 2/20 0.44
MAPT P10636 1/20 0.44
AKR1B1 P15121 2/20 0.43
CA7 P43166 2/20 0.43
CA13 Q8N1Q1 2/20 0.43
GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL6880906 0.83 MAOB (0.73) CA12CA9CA1MAOBALDH1A1
Hydrogen Sulfide SCHEMBL6880967 0.76 CYP2A6 (0.55) CA12CA9CA1MAOBALDH1A1
SCHEMBL3520931 0.76 MAOB (0.50) CA12CA9CA1MAOBALDH1A1
SCHEMBL6937941 0.75 KMT2A (0.50) ALDH1A1GAAKMT2AMEN1MAPT
SCHEMBL3523373 0.75 CA12 (0.58) CA12CA9CA1MAOBALDH1A1
SCHEMBL5671449 0.73 MAOB (0.45) CA12CA9CA1MAOBALDH1A1
SCHEMBL6877391 0.73 ALDH1A1 (0.47) CA12CA9CA1ALDH1A1MCL1
SCHEMBL3371438 0.73 CA12 (0.56) CA12CA9CA1MAOBALDH1A1
Hydrogen Sulfide SCHEMBL6878894 0.73 ALDH1A1 (0.44) CA12CA9CA1MAOBALDH1A1
SCHEMBL3918843 0.72 MEN1 (0.49) CA12CA9CA1MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed