Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA1 | P00915 | 7/20 | 1.00 |
| ▸ | CA9 | Q16790 | 7/20 | 1.00 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 3/20 | 0.59 |
| ▸ | CA3 | P07451 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL6880906 | 0.81 | MAOB (0.73) | CA12CA1CA9CA7CA5B | |
| SCHEMBL12304245 | 0.80 | CA12 (0.81) | CA12CA1CA9CA7CA5B | |
| SCHEMBL5638132 | 0.80 | CA12 (0.66) | CA12CA1CA9KDM4EGAA | |
| SCHEMBL8069545 | 0.79 | CA12 (0.63) | CA12CA1CA9CA7CA2 | |
| SCHEMBL12722467 | 0.79 | CA9 (0.64) | CA12CA1CA9KDM4EMAPT | |
| SCHEMBL5377371 | 0.77 | CA12 (0.61) | CA12CA1CA9CA7CA5B | |
| SCHEMBL23142698 | 0.77 | CA12 (0.62) | CA12CA1CA9CA7CA5B | |
| 7-Propoxycoumarin SCHEMBL6690398 | 0.75 | CA9 (1.00) | CA12CA1CA9CA7CA5B | |
| 7-Butoxycoumarin SCHEMBL6686295 | 0.75 | CA12 (1.00) | CA12CA1CA9CA7CA5B | |
| SCHEMBL24045405 | 0.74 | CA12 (0.82) | CA12CA1CA9CA7CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | claimed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | claimed |
| EP-3798215-A1 | COVALENT PRINTING BY PHOTO-TRIGGERED CLICK LIGATION | Université de Nantes (FR) | 2021-03-31 | — | — | EP | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2014-05-29 | — | — | US | disclosed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012070024-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | METASIGNAL THERAPEUTICS INC. (CA) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148400-A1 | CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY | CA7, CA4, CA2 | CA12 10/4885CA1 5/4885CA9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.