Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL4214895 | 1.00 | ALDH1A1 (0.55) | — | |
| Dimethyl Sulfoxide SCHEMBL3840626 | 0.96 | — | — | |
| Dimethyl Sulfoxide SCHEMBL28084771 | 0.96 | — | — | |
| Acetone SCHEMBL3757237 | 0.86 | ALDH1A1 (0.40) | — | |
| Propanol SCHEMBL526645 | 0.84 | — | — | |
| Dimethyl Sulfoxide SCHEMBL19995682 | 0.83 | ALDH1A1 (0.38) | — | |
| Dimethyl Sulfoxide SCHEMBL23041043 | 0.82 | TSHR (0.46) | — | |
| Dimethyl Sulfoxide SCHEMBL379695 | 0.82 | — | — | |
| Dimethyl Sulfoxide SCHEMBL27557207 | 0.80 | — | — | |
| Alcohol SCHEMBL2546349 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720465-A | Method for extracting effective components of lotus leaves | 陕西青溪生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117624044-A | Preparation method of lenvatinib | 山东新时代药业有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-114411282-B | Preparation method of high-strength skin-core structure porous aerogel fiber, product and application thereof | 江苏集萃先进纤维材料研究所有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117186339-A | Method for synthesizing phosphorylated microporous ionomer for fuel cell and method for preparing high-temperature proton exchange membrane by using same | 中国科学院大连化学物理研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-116565333-A | Preparation method of solid-state battery with integrated electrode | 北京理工大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116283726-A | Preparation method and application of cyanine dye variant and cyanine protein composite fluorophore | 吉林大学第一医院 | 2023-06-23 | — | — | CN | claimed |
| CN-116212120-A | Injectable self-healing hydrogel for bone repair and preparation method and application thereof | 武汉轻工大学 | 2023-06-06 | — | — | CN | claimed |
| CN-116115774-A | Double-layer multi-drug infinite coordination polymer anti-tumor composite nano-particle and preparation method thereof | 西安交通大学 | 2023-05-16 | — | — | CN | claimed |
| CN-115215856-A | Preparation method of PPAR delta agonist finadepa and intermediate thereof | 沈阳药科大学 | 2022-10-21 | — | — | CN | claimed |
| CN-110643354-B | Preparation method and application of tetraphenylethylene derivative/rare earth nanoparticle composite material for identifying variable-valence chromium ions | 山东大学 | 2022-09-06 | — | — | CN | claimed |
| EP-2001439-A2 | NANOEMULSIONS OF POORLY SOLUBLE PHARMACEUTICAL ACTIVE INGREDIENTS AND METHODS OF MAKING THE SAME | NOVAVAX, INC. (US) | 2008-12-17 | — | — | EP | claimed |
| CN-101198611-A | Phthalocyanine derivatives, process for their preparation, pharmaceutical compositions containing them, and their use | MOLTENI & C (IT) | 2008-06-11 | — | — | CN | claimed |
| US-20070264349-A1 | Nano-structured compositions and methods of making and using the same | NOVAVAX, INC. | 2007-11-15 | — | — | US | claimed |
| WO-2007123790-A1 | NANOSTRUCTURED COMPOSITIONS HAVING ANTIBACTERIAL, ANTI-FUNGAL, ANTI-YEAST, AND/OR ANTI-VIRAL PROPERTIES | NOVAVAX, INC. (US) | 2007-11-01 | — | — | WO | claimed |
| WO-2007103294-A2 | NANOEMULSIONS OF POORLY SOLUBLE PHARMACEUTICAL ACTIVE INGREDIENTS AND METHODS OF MAKING THE SAME | NOVAVAX, INC. (US) | 2007-09-13 | — | — | WO | claimed |
| CN-1253616-C | Water soluble polyvinyl alcohol fiber and its prepn and use | CHINA PETROCHEMICAL CORP (CN) | 2006-04-26 | — | — | CN | claimed |
| CN-1531555-A | Glycosaminoglycan derived from K5 polysaccharide and having high antithrombotic activity, and its preparation method | — | 2004-09-22 | — | — | CN | claimed |
| EP-0396069-B1 | Salts of azelastine having advanced solubility | ASTA MEDICA AG (DE) | 1994-06-22 | — | — | EP | claimed |
| EP-0396069-A1 | Salts of azelastine having advanced solubility | ASTA Medica Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | claimed |
| US-4031206-A | PEPTIDE ANTIBIOTICS, PSEUDONOCARDIA | PFIZER INC. (US) | 1977-06-21 | — | — | US | claimed |