Dimethyl Sulfoxide

Dimethyl Sulfoxide

SCHEMBL19995682

CCO.CO.C[S+](C)[O-].ClC(Cl)Cl

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

MAP2K1MAP2K2

The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Sulfoxide SCHEMBL28084771 0.87
Dimethyl Sulfoxide SCHEMBL1434942 0.87 LMNA (0.33)
Dimethyl Sulfoxide SCHEMBL16714296 0.83 LMNA (0.31)
Chloroform SCHEMBL6974119 0.83
Dimethyl Sulfoxide SCHEMBL688092 0.83
Dimethyl Sulfoxide SCHEMBL4214895 0.83 ALDH1A1 (0.55) ALDH1A1TSHR
Dimethyl Sulfoxide SCHEMBL3840626 0.79
Chloroform SCHEMBL2169183 0.79 TSHR (0.50) ALDH1A1TSHR
Chloroform SCHEMBL7542887 0.79 TSHR (0.60) ALDH1A1TSHR
Chloroform SCHEMBL8192102 0.79 TSHR (0.60) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018057649-A1 TAGGED POLY(ESTER AMIDE URETHANE)S, NANOPARTICLES FORMED FROM SAME, AND USES THEREOF CORNELL UNIVERSITY (US) 2018-03-29 WO disclosed