Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6881209

O=c1ccc2c(OS(=O)(=O)C(F)(F)F)cccc2o1.S

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.55
KCNA3 P22001 2/20 0.49
CYP3A4 P08684 3/20 0.48
ALOX15 P16050 2/20 0.39
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAOB P27338 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
DRD2 P14416 3/20 0.34
DRD4 P21917 2/20 0.34
DRD3 P35462 2/20 0.34
HTR5A P47898 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464810 0.99 CYP2A6 (0.56) CYP2A6KCNA3CYP3A4ALOX15KDM4E
Hydrogen Sulfide SCHEMBL6868834 0.85 CYP2A6 (0.49) CYP2A6KCNA3CYP3A4ALOX15KDM4E
SCHEMBL12986005 0.81 KCNA3 (0.51) KCNA3ALOX15ALDH1A1L3MBTL1MAOB
SCHEMBL30751952 0.79 MAOA (0.40) CYP2A6KCNA3KDM4EALDH1A1DRD2
SCHEMBL16904155 0.79 KDM4E (0.43) CYP2A6CYP3A4KDM4EALDH1A1GLA
SCHEMBL3928046 0.78 KCNA3 (0.46) KCNA3MAOBDRD2DRD4DRD3
SCHEMBL18795081 0.77 CDC14B (0.46) CYP2A6CYP3A4KDM4EALDH1A1GLA
SCHEMBL2987667 0.76 AR (0.40) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL29706003 0.76 MEN1 (0.42) DRD2DRD4DRD3HTR5A
SCHEMBL203899 0.76 MEN1 (0.42) DRD2DRD4DRD3HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed