SCHEMBL203899

SCHEMBL203899

O=S(=O)(Oc1cccc2c(OS(=O)(=O)C(F)(F)F)cccc12)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
ESR1 P03372 2/20 0.42
GAA P10253 2/20 0.42
KMT2A Q03164 2/20 0.42
ESR2 Q92731 2/20 0.42
DRD2 P14416 12/20 0.42
DRD3 P35462 9/20 0.42
DRD4 P21917 7/20 0.42
HTR5A P47898 1/20 0.42
DRD1 P21728 5/20 0.40
DRD5 P21918 5/20 0.40
HTR1D P28221 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706003 1.00 MEN1 (0.42) MEN1ESR1GAAKMT2AESR2
SCHEMBL6851155 0.92 MEN1 (0.38) MEN1ESR1GAAKMT2AESR2
SCHEMBL3222252 0.91 ESR1 (0.55) MEN1ESR1GAAKMT2AESR2
SCHEMBL15307384 0.91 MEN1 (0.41) MEN1ESR1GAAKMT2AESR2
SCHEMBL12476299 0.91 MEN1 (0.41) MEN1ESR1GAAKMT2AESR2
SCHEMBL9999646 0.89 MEN1 (0.49) MEN1ESR1GAAKMT2AESR2
SCHEMBL6812319 0.89 ALDH1A1 (0.43) MEN1ESR1GAAKMT2AESR2
SCHEMBL5372354 0.89 CYP1A2 (0.43) MEN1ESR1GAAKMT2AESR2
SCHEMBL29937164 0.89 ALDH1A1 (0.46) MEN1ESR1GAAKMT2AESR2
SCHEMBL1056365 0.89 ALDH1A1 (0.46) MEN1ESR1GAAKMT2AESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12049542-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2024-07-30 US disclosed
US-20230140877-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-11 US disclosed
US-20230140877-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-11 US disclosed
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-04 US disclosed
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same LG CHEM, LTD. (KR) 2023-05-04 US disclosed
US-20210163683-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-06-03 US disclosed
US-20210163683-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-06-03 US disclosed
EP-2597932-B1 MANUFACTURING METHOD FOR ORGANIC LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL CO (JP) 2021-04-14 EP disclosed
CN-106588890-B Antiviral compounds 吉利德制药有限责任公司 2020-11-27 CN disclosed
EP-3626716-A1 ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2020-03-25 EP disclosed
WO-2010132601-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-11-18 WO disclosed
US-20090045730-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-02-19 US disclosed
US-20090045730-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-02-19 US disclosed
US-20090045730-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-02-19 US disclosed
US-20090008606-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090008605-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
EP-0696287-B1 UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION PHARMACIA & UPJOHN SPA (IT) 2000-03-08 EP disclosed
US-5700788-A Ureido derivatives of naphthalenephosphonic acids PHARMACIA & UPJOHN S.P.A. (IT) 1997-12-23 US disclosed
EP-0696287-A1 UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION PHARMACIA & UPJOHN S.p.A. (IT) 1996-02-14 EP disclosed
WO-1995023806-A2 UREIDO DERIVATIVES OF NAPHTHALENEPHOSPHONIC ACIDS AND PROCESS FOR THEIR PREPARATION PHARMACIA S.P.A. (IT) 1995-09-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140749-A1 Novel Compound and Organic Light Emitting Device Comprising the Same ARL1, LAS1L, AR MEN1 1101/4885ESR1 23/4885GAA 3263/4885
US-20090008606-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME NAP1L4, NAP1L1, ARL1 MEN1 689/4885ESR1 238/4885GAA 4145/4885
US-20090008605-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME NAP1L1, NAP1L4, NAT1 MEN1 487/4885ESR1 241/4885GAA 4352/4885
US-20090045730-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, RFT1, RIF1 MEN1 1324/4885ESR1 164/4885GAA 4250/4885
US-20230140877-A1 Novel Compound and Organic Light Emitting Device Comprising the Same CRY2, CRY1, GLI1 MEN1 1050/4885ESR1 46/4885GAA 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.