Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881487 | 1.00 | MAPT (0.44) | MAPTTRPA1NFE2L2FOSJUN | |
| SCHEMBL6871427 | 0.81 | ALOX15 (0.53) | MAPTTRPA1FGF23ALDH1A1SMN1; SMN2 | |
| SCHEMBL6871430 | 0.81 | ALOX15 (0.53) | MAPTTRPA1FGF23ALDH1A1SMN1; SMN2 | |
| SCHEMBL6879390 | 0.81 | F3 (0.53) | MAPTNFE2L2ALDH1A1CYP3A4HPGD | |
| SCHEMBL6879391 | 0.81 | F3 (0.53) | MAPTNFE2L2ALDH1A1CYP3A4HPGD | |
| SCHEMBL6871311 | 0.81 | HDAC8 (0.41) | MAPTTRPA1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6871314 | 0.81 | HDAC8 (0.41) | MAPTTRPA1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6870578 | 0.76 | FOS (0.41) | MAPTFOSJUNALDH1A1CYP3A4 | |
| SCHEMBL6870577 | 0.76 | FOS (0.41) | MAPTFOSJUNALDH1A1CYP3A4 | |
| SCHEMBL10925881 | 0.74 | MAPT (0.56) | MAPTFOSJUNALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703182-B1 | PHOTOPOLYMERISABLE COMPOSITIONS COMPRISING SAID COMPOUNDS AND USE OF THE COMPOUNDS AS LATENT ACIDS, WHICH CAN BE ACTIVATED BY IRRADIATION WITH LIGHT | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-03-09 | — | — | US | disclosed |
| EP-1105373-B1 | UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS | CIBA SC HOLDING AG (CH) | 2002-10-09 | — | — | EP | disclosed |
| EP-1105373-A1 | UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS | Ciba SC Holding AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010972-A1 | NEW UNSATURATED OXIME DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-02 | — | — | WO | disclosed |