Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881648 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL6881645 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL6879793 | 0.88 | HTT (0.49) | ALDH1A1MEN1KMT2ACASP1HTT | |
| SCHEMBL6879786 | 0.88 | HTT (0.49) | ALDH1A1MEN1KMT2ACASP1HTT | |
| SCHEMBL6879783 | 0.88 | HTT (0.49) | ALDH1A1MEN1KMT2ACASP1HTT | |
| SCHEMBL6852491 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL6852496 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL6852224 | 0.81 | KMT2A (0.44) | ALDH1A1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL6879090 | 0.81 | KMT2A (0.44) | ALDH1A1MEN1KMT2AHTTHDAC6 | |
| SCHEMBL6852222 | 0.81 | KMT2A (0.44) | ALDH1A1MEN1KMT2AHTTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |