Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 4/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387110 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL6881661 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL25243333 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL1309656 | 0.71 | GSR (0.41) | ALDH1A1LMNAMEN1BLMKMT2A | |
| SCHEMBL2448267 | 0.71 | GSR (0.41) | ALDH1A1LMNAMEN1BLMKMT2A | |
| SCHEMBL11277663 | 0.70 | — | — | |
| SCHEMBL7106567 | 0.70 | MME (0.46) | ALDH1A1MAPTMMEACEHPGD | |
| SCHEMBL2183607 | 0.69 | KDM4E (0.34) | MAPTPTGS2MAPK1BLM | |
| SCHEMBL197221 | 0.68 | MAPT (0.50) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL80875 | 0.68 | MAPT (0.50) | ALDH1A1MAPTLMNAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144170-B1 | BIOSYNTHESIS OF UNNATURAL CEPHALOSPORINS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1989-01-25 | — | — | EP | claimed |
| EP-0144170-A1 | Biosynthesis of unnatural cephalosporins | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1985-06-12 | — | — | EP | claimed |
| EP-1427441-A2 | COMPOSITE SUPERIMMUNOGEN FOR BI-FUNCTIONAL VACCINE USE FOR THE TREATMENT OF ILLNESSES ASSOCIATED WITH A STROMAL TISSUE DISORDER | NEOVACS (FR) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003013593-A2 | COMPOSITE SUPERIMMUNOGEN FOR BI-FUNCTIONAL VACCINE USE FOR THE TREATMENT OF ILLNESSES ASSOCIATED WITH A STROMAL TISSUE DISORDER | NEOVACS (FR) | 2003-02-20 | — | — | WO | disclosed |