Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881661 | 0.72 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL6881655 | 0.72 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9069027 | 0.72 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL3387110 | 0.72 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL28536446 | 0.71 | LDHA (0.41) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL16267390 | 0.70 | — | — | |
| SCHEMBL987124 | 0.69 | — | — | |
| SCHEMBL3621769 | 0.68 | — | — | |
| SCHEMBL161143 | 0.67 | — | — | |
| SCHEMBL3179343 | 0.67 | LDHA (0.37) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204441-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-07-05 | — | — | EP | disclosed |