Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870646 | 1.00 | HTT (0.47) | HTTLMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL27487569 | 0.96 | HTT (0.50) | HTTLMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28693899 | 0.86 | HPGD (0.53) | HTTLMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28306573 | 0.79 | HPGD (0.54) | LMNAHPGDMEN1TP53KMT2A | |
| SCHEMBL1826062 | 0.79 | HPGD (0.54) | LMNAHPGDMEN1TP53KMT2A | |
| SCHEMBL2924871 | 0.72 | CA2 (0.52) | HPGDALDH1A1CA12CA1CA9 | |
| SCHEMBL16086852 | 0.72 | HPGD (0.44) | HTTLMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28306598 | 0.72 | HPGD (0.50) | LMNAHPGDMEN1TP53KMT2A | |
| SCHEMBL28684147 | 0.69 | HPGD (0.52) | LMNAHPGDMEN1TP53KMT2A | |
| SCHEMBL27774938 | 0.68 | HRH3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824707-B2 | MIXTURE CONTAINING DOPE | CLARIANT INTERNATIONAL LTD. (CH) | 2004-11-30 | — | — | US | disclosed |
| EP-1367114-A1 | Active matrix liquid crystal device and smectic liquid crystal mixture | Clariant International Ltd. (CH) | 2003-12-03 | — | — | EP | disclosed |
| US-20030127627-A1 | Active matrix liquid crystal device and smectic liquid crystal mixture | CLARIANT INTERNATIONAL LTD. | 2003-07-10 | — | — | US | disclosed |