Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.65 |
| ▸ | CCR1 | P32246 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604508 | 0.90 | ELANE (0.81) | ELANECCR1MEN1KMT2ANPSR1 | |
| SCHEMBL8219783 | 0.88 | ELANE (0.66) | ELANECCR1MEN1KMT2ANPSR1 | |
| Acetic Acid SCHEMBL1603712 | 0.88 | ELANE (0.76) | ELANECCR1MEN1KMT2ANPSR1 | |
| SCHEMBL6882889 | 0.86 | ELANE (0.59) | ELANECCR1MEN1KMT2ANPSR1 | |
| SCHEMBL1604898 | 0.86 | ELANE (0.78) | ELANECCR1MEN1KMT2ANPSR1 | |
| Bromide SCHEMBL1603849 | 0.85 | ELANE (0.77) | ELANECCR1MEN1KMT2ANPSR1 | |
| SCHEMBL1604290 | 0.85 | ELANE (0.77) | ELANECCR1MEN1KMT2ANPSR1 | |
| Iodide SCHEMBL1603024 | 0.85 | ELANE (0.76) | ELANECCR1MEN1KMT2ANPSR1 | |
| Acetic Acid SCHEMBL1604206 | 0.84 | ELANE (0.74) | ELANECCR1MEN1KMT2ANPSR1 | |
| SCHEMBL27872087 | 0.82 | ELANE (0.82) | ELANECCR1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011039528-A1 | 2-PYRIDONE COMPOUNDS USED AS INHIBITORS OF NEUTROPHIL ELASTASE | ASTRAZENECA AB (SE) | 2011-04-07 | — | — | WO | disclosed |