Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706841 | 0.84 | TRPA1 (0.37) | LMNAL3MBTL1TDP1TRPA1TSHR | |
| SCHEMBL6839625 | 0.84 | TSHR (0.41) | LMNATRPA1TSHRALDH1A1ALOX15 | |
| SCHEMBL1904032 | 0.83 | TRPA1 (0.45) | LMNATDP1TRPA1TSHRTHRB | |
| Adonitol SCHEMBL27590136 | 0.78 | LMNA (0.50) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL19327340 | 0.76 | TSHR (0.46) | LMNATDP1TRPA1TSHRTHRB | |
| SCHEMBL15484287 | 0.75 | LMNA (0.53) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL16745483 | 0.75 | LMNA (0.53) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL16745482 | 0.75 | LMNA (0.53) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL16745478 | 0.75 | LMNA (0.53) | LMNAL3MBTL1TDP1TSHRKDM4E | |
| SCHEMBL16745484 | 0.75 | LMNA (0.53) | LMNAL3MBTL1TDP1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426391-A1 | Aqueous polyurethane dispersions and their use for preparation of coatings that are permeable to water vapor | UCB, S.A. (BE) | 2004-06-09 | — | — | EP | disclosed |