Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688029 | 0.91 | CTSA (0.42) | CTSAGAANPSR1MEN1KMT2A | |
| SCHEMBL687038 | 0.87 | SMN1; SMN2 (0.43) | GAANPSR1MEN1KMT2ALMNA | |
| SCHEMBL686977 | 0.86 | SLC16A3 (0.42) | GAANPSR1MEN1KMT2ALMNA | |
| SCHEMBL687999 | 0.86 | SLC16A3 (0.42) | CTSAGAANPSR1MEN1KMT2A | |
| SCHEMBL686806 | 0.84 | PTGER3 (0.45) | CTSAP2RY14MAPTPTGER3 | |
| SCHEMBL687875 | 0.84 | CTSA (0.40) | CTSASMN1; SMN2CYP26A1MAPT | |
| SCHEMBL686808 | 0.83 | CTSA (0.42) | CTSASMN1; SMN2MAPTPTGER3ALDH1A1 | |
| SCHEMBL686896 | 0.83 | PTGER3 (0.44) | CTSAP2RY14PTGER3 | |
| SCHEMBL29371834 | 0.83 | PTGER3 (0.44) | CTSAP2RY14PTGER3 | |
| SCHEMBL686663 | 0.83 | PTGER3 (0.44) | CTSAP2RY14MAPTPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |