Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687999 | 0.95 | SLC16A3 (0.42) | SLC16A3SLC16A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL687038 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL688267 | 0.86 | CTSA (0.43) | SMN1; SMN2MEN1KMT2ANPSR1LMNA | |
| SCHEMBL687640 | 0.85 | PTGER3 (0.40) | SLC16A3SLC16A1NPSR1LMNAGAA | |
| SCHEMBL688067 | 0.84 | SLC22A12 (0.39) | SLC16A3SLC16A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL687324 | 0.82 | PTGER3 (0.41) | SLC16A3SLC16A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL687275 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL687744 | 0.80 | PTGER3 (0.43) | SLC16A3SLC16A1NPSR1LMNAGAA | |
| SCHEMBL688409 | 0.80 | PPARG (0.42) | SLC16A3SLC16A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL688029 | 0.79 | CTSA (0.42) | SMN1; SMN2MEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |