Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1905698 | 0.95 | MASP2 (0.42) | MASP2ALDH1A1LMNAFURINKIT | |
| SCHEMBL1433675 | 0.87 | MASP2 (0.43) | MASP2ALDH1A1LMNAFURINKIT | |
| SCHEMBL3157818 | 0.87 | MASP2 (0.43) | MASP2ALDH1A1LMNAFURINKIT | |
| SCHEMBL1432429 | 0.87 | CYP3A4 (0.42) | MASP2PPIBCYP3A4 | |
| SCHEMBL1905699 | 0.86 | MASP2 (0.39) | MASP2ALDH1A1LMNAFURINKIT | |
| SCHEMBL1432393 | 0.85 | MASP2 (0.43) | MASP2CPB2PPIBCPB1EPHX1 | |
| SCHEMBL1432406 | 0.85 | MASP2 (0.43) | MASP2CPB2PPIBCPB1EPHX1 | |
| SCHEMBL1431929 | 0.84 | MASP2 (0.46) | MASP2ALDH1A1LMNAKITMAPK14 | |
| SCHEMBL1432628 | 0.84 | MASP2 (0.42) | MASP2FURINKITMAPK14CPB2 | |
| SCHEMBL1432619 | 0.84 | MASP2 (0.42) | MASP2FURINKITMAPK14CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |