Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 4/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1905698 | 0.86 | MASP2 (0.42) | MASP2PPIBFURINCPB2KIT | |
| SCHEMBL6882736 | 0.86 | MASP2 (0.43) | MASP2PPIBFURINCPB2KIT | |
| SCHEMBL1432429 | 0.84 | CYP3A4 (0.42) | MASP2PPIBREN | |
| SCHEMBL1433675 | 0.81 | MASP2 (0.43) | MASP2PPIBFURINCPB2KIT | |
| SCHEMBL3157818 | 0.81 | MASP2 (0.43) | MASP2PPIBFURINCPB2KIT | |
| SCHEMBL3153401 | 0.79 | REN (0.48) | REN | |
| SCHEMBL3153410 | 0.79 | REN (0.48) | REN | |
| SCHEMBL3153397 | 0.79 | REN (0.48) | REN | |
| SCHEMBL1432393 | 0.79 | MASP2 (0.43) | MASP2PPIBCPB2CPB1 | |
| SCHEMBL1432406 | 0.79 | MASP2 (0.43) | MASP2PPIBCPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |