⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL518873 | 0.93 | — | — | |
| SCHEMBL433101 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL3178430 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL3187913 | 0.90 | CA1 (0.38) | — | |
| SCHEMBL362475 | 0.86 | — | — | |
| SCHEMBL491332 | 0.72 | APLNR (0.35) | — | |
| SCHEMBL5423 | 0.69 | — | — | |
| SCHEMBL24797747 | 0.69 | — | — | |
| SCHEMBL14837609 | 0.67 | — | — | |
| SCHEMBL390796 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269737-A1 | 7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-03 | — | — | US | claimed |
| EP-2323980-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | Boehringer Ingelheim International GmbH (DE) | 2011-05-25 | — | — | EP | claimed |
| WO-2010026096-A1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | claimed |
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | claimed |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-03-10 | — | — | US | claimed |
| EP-0906291-B1 | SUBSTITUTED PHENYL URACILS | BAYER CROPSCIENCE AG (DE) | 2005-03-09 | — | — | EP | claimed |
| US-6825183-B2 | CONTROLLING PLANTS; ANTIGROWTH AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | claimed |
| EP-1244634-B1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | claimed |
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-26 | — | — | US | claimed |
| EP-1244634-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AG (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047894-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| US-6245714-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-12 | — | — | US | claimed |
| EP-0906291-A1 | SUBSTITUTED PHENYL URACILS | BAYER AG (DE) | 1999-04-07 | — | — | EP | claimed |
| WO-1997045418-A1 | SUBSTITUTED PHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | claimed |
| EP-4371979-A1 | FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| EP-3395583-B1 | HEAT-SENSITIVE RECORDING MATERIAL | NIPPON KAYAKU KK (JP) | 2024-03-27 | — | — | EP | disclosed |
| CN-113226310-B | 15-PGDH inhibitors | 杏林制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |