Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741847 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2TSHRALDH1A1TAAR1MEN1 | |
| SCHEMBL28315549 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL21269521 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL21269478 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL28314443 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL28875971 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL21269477 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL28314702 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL28314546 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1ATRPA1CES1TSHR | |
| SCHEMBL28314666 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1ATRPA1CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042372-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SPA (IT) | 2004-07-14 | — | — | EP | claimed |