Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339774 | 0.88 | MAPT (0.52) | KDM4ERECQLMAPTPRSS1RAB9A | |
| SCHEMBL5311543 | 0.82 | KDM4E (0.44) | KDM4ERECQLMAPTPRSS1RAB9A | |
| SCHEMBL12703538 | 0.81 | KDM4E (0.61) | KDM4ERECQLMAPTL3MBTL1 | |
| SCHEMBL3611926 | 0.81 | KDM4E (0.61) | KDM4ERECQLMAPTL3MBTL1 | |
| SCHEMBL13554406 | 0.81 | CYP3A4 (0.50) | KDM4ERECQLMAPT | |
| SCHEMBL12093635 | 0.81 | CA12 (0.55) | KDM4EMAPTRAB9AL3MBTL1 | |
| SCHEMBL1805600 | 0.79 | LTA4H (0.57) | RAB9A | |
| SCHEMBL294683 | 0.79 | LTA4H (0.55) | KDM4EMAPTRAB9ANQO1L3MBTL1 | |
| SCHEMBL6445608 | 0.79 | DRD2 (0.55) | KDM4ERECQLMAPTL3MBTL1 | |
| SCHEMBL10729488 | 0.78 | IDO1 (0.59) | KDM4ERECQLMAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-B1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR INC (US) | 2004-01-14 | — | — | EP | disclosed |