Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881731 | 0.86 | DRD4 (0.52) | ALDH1A1LMNAHTTKDM4ETDP1 | |
| SCHEMBL6881816 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL6883746 | 0.85 | DRD4 (0.51) | ALDH1A1TSHRLMNAHTTKDM4E | |
| SCHEMBL6878952 | 0.85 | DRD4 (0.51) | ALDH1A1HTTKDM4EHPGDDRD4 | |
| SCHEMBL6878954 | 0.82 | DRD4 (0.52) | ALDH1A1HTTKDM4EHPGDDRD4 | |
| SCHEMBL6880280 | 0.80 | HPGD (0.67) | ALDH1A1HTTKDM4EHSD17B10HPGD | |
| SCHEMBL6880423 | 0.79 | DRD4 (0.54) | ALDH1A1HTTKDM4EHPGDDRD4 | |
| SCHEMBL6881533 | 0.76 | DRD4 (0.49) | ALDH1A1HTTKDM4EHPGDDRD4 | |
| SCHEMBL3398060 | 0.73 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL6874013 | 0.73 | DRD4 (0.56) | ALDH1A1KDM4EDRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | TRIMERIS, INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2004043913-A2 | HETERO-SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040166137-A1 | Hetero-substituted benzimidazole compounds and antiviral uses thereof | MAVS, TIMM13, TIMM10 | ALDH1A1 3062/4885MEN1 4683/4885KMT2A 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.