Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564253 | 0.82 | ALDH1A1 (0.43) | MAOBMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL23250015 | 0.76 | MAPT (0.49) | MAOBMAOAMAPTRAB9AKDM4E | |
| SCHEMBL6885431 | 0.75 | ALOX5AP (0.33) | MAOBMAOAMAPK1NPC1RAB9A | |
| SCHEMBL6885428 | 0.75 | ALOX5AP (0.33) | MAOBMAOAMAPK1NPC1RAB9A | |
| SCHEMBL21543853 | 0.74 | TDP1 (0.55) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7765941 | 0.73 | SMPD1 (0.56) | MAOBMAOAMAPTALDH1A1NPC1 | |
| SCHEMBL8588735 | 0.72 | MAOB (0.53) | MAOBMAOAMAPTRAB9AKDM4E | |
| SCHEMBL22907331 | 0.71 | MAPT (0.50) | MAOBMAOAMAPTALDH1A1MAPK1 | |
| SCHEMBL29548458 | 0.71 | MAPT (0.50) | MAOBMAOAMAPTALDH1A1MAPK1 | |
| SCHEMBL27571102 | 0.71 | MAOB (0.64) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |