Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 13/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687559 | 0.88 | ALDH1A1 (0.49) | CTSAPOLBALDH1A1 | |
| SCHEMBL687449 | 0.85 | CTSA (0.47) | CTSAPOLB | |
| SCHEMBL687335 | 0.83 | CTSA (0.43) | CTSAPOLB | |
| SCHEMBL687896 | 0.82 | CTSA (0.41) | CTSAPOLB | |
| SCHEMBL688035 | 0.82 | CTSA (0.41) | CTSAPOLBALDH1A1RXFP1 | |
| SCHEMBL687690 | 0.81 | CTSA (0.44) | CTSA | |
| SCHEMBL687511 | 0.81 | MEN1 (0.46) | CTSAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL688264 | 0.81 | LCK (0.47) | CTSAPOLBMAPK1ALDH1A1RXFP1 | |
| SCHEMBL687280 | 0.81 | POLB (0.43) | CTSAPOLB | |
| SCHEMBL687925 | 0.80 | CYP26A1 (0.42) | CTSAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |