Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26412447 | 0.77 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7589274 | 0.77 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2662880 | 0.77 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6745027 | 0.76 | ESR1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30299161 | 0.75 | BCL2L1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL691510 | 0.74 | ESR1 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24075195 | 0.73 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| Ethylgallate SCHEMBL39599 | 0.73 | SERPINE1 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13266684 | 0.73 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL190911 | 0.73 | CA12 (0.72) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471063-A1 | Compounds and methods of treating cell proliferative diseases, retinopathies and arthritis | Exonhit Therapeutics S.A. (FR) | 2004-10-27 | — | — | EP | disclosed |