Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595464 | 0.91 | ESR1 (0.59) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL6745027 | 0.91 | ESR1 (0.59) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL5026774 | 0.88 | ESR1 (0.56) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL8950683 | 0.86 | CA12 (0.60) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL6640579 | 0.83 | CA12 (0.56) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL31556327 | 0.83 | CA12 (0.56) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL9328767 | 0.83 | CA12 (0.56) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL13011349 | 0.83 | ESR1 (0.58) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7634356 | 0.82 | ESR1 (0.50) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL3243690 | 0.81 | ALDH1A1 (0.57) | ESR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354616-B | Diaryl-1, 2, 4-triazole compound and preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |
| CN-111662239-B | 1,2, 4-triazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |
| CN-113354616-A | Diaryl-1, 2, 4-triazole compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2021-09-07 | — | — | CN | disclosed |
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| CN-111662239-A | 1,2, 4-triazole compound and preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2020-09-15 | — | — | CN | disclosed |
| EP-2125797-B1 | AMINO- PYRIDINE DERIVATIVES AS S1P1 /EDG1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2014-01-15 | — | — | EP | disclosed |
| US-8592460-B2 | Amino-pyridine derivatives as S1P1 /EDG1 receptor agonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-11-26 | — | — | US | disclosed |
| EP-2118067-B1 | NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | SIENA BIOTECH SPA (IT) | 2013-05-08 | — | — | EP | disclosed |
| EP-1466912-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2013-04-24 | — | — | EP | disclosed |
| EP-2560643-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING 1,3,4-OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-0277589-B1 | COLOR PHOTOGRAPHS, A PROCESS FOR PREPARING THEM AND COLOR PHOTOGRAPHIC MATERIALS EMPLOYED THEREFOR | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0258662-B1 | COLOR PHOTOGRAPHS AND METHOD FOR PREPARATION OF THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5098805-A | Nondiscoloring photographic films | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5047315-A | Color-stain prevention | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| US-4945164-A | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof | STERLING DRUG INC. (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0277589-A2 | Color photographs, a process for preparing them and color photographic materials employed therefor | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0258662-A2 | Color photographs and method for preparation of the same | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4027018-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4000270-A | INSECTIDES, ACARICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3954919-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | ESR1 4000/4885CA12 2396/4885CA1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.