SCHEMBL6883659

SCHEMBL6883659

N#CC(c1ccccc1)C(C#N)c1ccc(CBr)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TRPA1 O75762 2/20 0.48
TSHR P16473 2/20 0.48
ESR1 P03372 7/20 0.45
ESR2 Q92731 7/20 0.45
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
MAP2K1 Q02750 1/20 0.39
CYP1A2 P05177 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 3/20 0.34
KDM4E B2RXH2 1/20 0.34
HTR2A P28223 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6309534 0.81 ESR1 (0.56) ALDH1A1TRPA1TSHRESR1ESR2
SCHEMBL819626 0.81 ESR1 (0.56) ALDH1A1TRPA1TSHRESR1ESR2
SCHEMBL9127626 0.78 ESR2 (0.56) ALDH1A1TRPA1TSHRESR1ESR2
SCHEMBL3108222 0.77 TSHR (0.59) ALDH1A1TRPA1TSHRCES2CES1
SCHEMBL7711210 0.77 ESR1 (0.44) ALDH1A1TRPA1TSHRESR1ESR2
SCHEMBL7716670 0.72 ESR2 (0.36) ALDH1A1TRPA1TSHRESR1ESR2
Benzyl Bromide SCHEMBL28292772 0.72 ALDH1A1 (0.74) ALDH1A1TRPA1TSHRCES2CES1
SCHEMBL5972955 0.71 TRPA1 (0.58) ALDH1A1TRPA1TSHRESR1ESR2
SCHEMBL8102784 0.71 TSHR (0.58) ALDH1A1TRPA1TSHRESR1ESR2
Benzyl Bromide SCHEMBL28027277 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490330-A2 POLYMER BOUND DONOR-ACCEPTOR-DONOR COMPOUNDS AND THEIR USE IN A 3-DIMENSIONAL OPTICAL MEMORY Mempile Inc. (US) 2004-12-29 EP disclosed
WO-2003070689-A2 POLYMER BOUND DONOR-ACCEPTOR-DONOR COMPOUNDS AND THEIR USE IN A 3-DIMENSIONAL OPTICAL MEMORY MEMPILE INC. (US) 2003-08-28 WO disclosed