Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 15/20 | 0.67 |
| ▸ | PHOSPHO1 | Q8TCT1 | 14/20 | 0.67 |
| ▸ | PMM2 | O15305 | 13/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | G6PD | P11413 | 4/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896513 | 0.87 | MPI (0.65) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL26645117 | 0.85 | MPI (0.64) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL1899594 | 0.81 | MPI (0.74) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL12252300 | 0.80 | MPI (1.00) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL1895902 | 0.78 | MPI (0.60) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL8370795 | 0.74 | G6PD (0.69) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL25763324 | 0.73 | MPI (0.89) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL29864440 | 0.73 | MPI (0.54) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL1897990 | 0.73 | G6PD (1.00) | MPIPHOSPHO1PMM2RAB9AG6PD | |
| SCHEMBL1900552 | 0.72 | MPI (0.74) | MPIPHOSPHO1PMM2RAB9AG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011062864-A2 | INHIBITORS OF NOX ENZYMES AND METHODS OF USE THEREOF | EMORY UNIVERSITY (US) | 2011-05-26 | — | — | WO | disclosed |