SCHEMBL6883872

SCHEMBL6883872

CCC(CC)(CC/C=C(\C)c1ccc(COc2ccc(C(=O)OC)c(C(=O)OC)c2)s1)O[Si](CC)(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.34
ALOX5AP P20292 2/20 0.34
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6883874 1.00 MRGPRX4 (0.34) MRGPRX4ALOX5APTDP1
SCHEMBL6562805 0.90 MRGPRX4 (0.31) MRGPRX4
SCHEMBL6562808 0.90 MRGPRX4 (0.31) MRGPRX4
SCHEMBL6889766 0.86 MRGPRX4 (0.37) MRGPRX4ALOX5APTDP1
SCHEMBL6889768 0.86 MRGPRX4 (0.37) MRGPRX4ALOX5APTDP1
SCHEMBL6887141 0.86 ALOX5AP (0.33) ALOX5APTDP1
SCHEMBL6887145 0.86 ALOX5AP (0.33) ALOX5APTDP1
SCHEMBL6883573 0.86 ALOX5AP (0.32) ALOX5APTDP1
SCHEMBL6883569 0.86 ALOX5AP (0.32) ALOX5APTDP1
SCHEMBL6890035 0.79 ALOX5AP (0.33) ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706725-B1 BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-03-16 US disclosed